Aunt's approx. $45,000 home. Do they need to probate will?

If your wife and brother are not on the title you are likely going to need to probate the will. You may wish to talk to a Title company to see if they can sell the property under Texas law without probate. I that case there would be little advantage of doing the probate because some attorney will eat up all of the profit. When you are ready to sell the house you should go talk to a tax professional to get some advise as there may not be a tax debt to worry about.